Colon and rectal cancer is collectively termed colorectal cancer. A recent study has proved that regular consumption of baby aspirin, i.e., 15 tablets per month before colorectal cancer diagnosis, considerably increases the chances of survival.
The large intestine is approximately 5 feet in length and is made of the colon and rectum, which form a part of the digestive system named the GI system of the human body.
The large intestine can be further divided into two types:
1. Proximal Colon- The uppermost part of the large intestine
2. Distal Colon- The lowest part of the large intestine
Uncontrollable growth of cells forms polyp-like masses on the inner lining of the colon and rectum, which can result in colorectal cancer over the course of many years.
The cancerous cells grow further, invading the patient’s blood vessels and lymph nodes.
Baby Aspirin is a low dosage tablet that reduces the risk of death in patients affected by colorectal cancer by inhibiting the growth of the polyps.
Tumors are cells that are clumped together due to the high production of an enzyme called thromboxane A2 by the blood platelets. Aspirin destroys the life-cycle of these platelets by thinning the blood and deactivates the production of the enzyme that promotes colorectal cancer.
The said study published in the Journal of the National Cancer Institute monitored around 2500 participants till December 2016 who enrolled themselves in 1992 or 1993.
The participants who consumed aspirin and non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) showed that all the participants did get colorectal cancer. But it was observed that the patients who consumed aspirin regularly had higher chances of survival as their tumors never metastasized at the same speed as non-aspirin consumers.
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